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. 2021 Feb 3;12(3):413–419. doi: 10.1021/acsmedchemlett.0c00611

Table 1. Preliminary Antibacterial Screeninga.

  S. aureus
 E. faecalis
 S. pneumoniae E. coli C. difficile
compound ATCC 29213 NCTC 10442b Mu50c ATCC 29212 ATCC 51299d ATCC 49619 ATCC 10418 ATCC 700057 NSW 132 (RT027)e
1 2 2 4 4 8 1 4 16 8
2 2 2 2 2 8 1 2 16 16
3 4 2 4 4 8 1 4 16 16
4 4 4 2 4 8 2 4 16 8
5 4 4 4 4 8 2 4 16 16
6 4 8 2 4 8 2 32 16 16
7 2 4 4 4 16 1 8 16 8
8 4 4 4 4 16 4 16 32 16
9 4 4 4 8 16 2 32 16 8
vancomycin 1 1 8 2 >8 0.5 >8 1 0.5
colistin - - - - - - 1 - -
a

Values are reported as MIC values in μg/mL.

b

Methicillin-resistant S. aureus (MRSA).

c

Vancomycin intermediate susceptibility S. aureus (VISA).

d

Vancomycin-resistant E. faecalis (VRE).

e

C. difficile PCR Ribotype 027 (RT027).