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. 2021 Feb 3;12(3):413–419. doi: 10.1021/acsmedchemlett.0c00611

Table 2. Secondary Antimicrobial Screeninga (Bacteria and Fungi).

  S. aureus P. aeruginosa K. pneumoniae A. baumannii E. coli C. albicans C. neoformans var. grubii
compound ATCC 43300b ATCC 27853 ATCC 700603c ATCC 19606 ATCC 25922 ATCC 90028 ATCC 208821
1 ≤0.25 16 32 16 8 32 >32
2 ≤0.25 8 >32 4 8 32 >32
3 ≤0.25 8 32 4 4 >32 >32
4 ≤0.25 2 >32 16 2 16 >32
5 ≤0.25 32 >32 32 32 8 >32
6 ≤0.25 16 32 32 8 8 >32
7 ≤0.25 8 32 4 8 16 >32
8 ≤0.25 32 >32 32 32 16 >32
9 ≤0.25 8 32 32 8 1 >32
vancomycin 1 - - - - - -
colistin - 0.25 0.25 0.25 0.125 - -
fluconazole - - - - - 0.125 8
amphotericin B - - - - - 1.56 1.56
a

Testing performed by the Community for Open Antimicrobial Drug Discovery (CO-ADD) – values are reported as MIC values in μg/mL.

b

Methicillin-resistant S. aureus (MRSA).

c

Multidrug-resistant K. pneumoniae.