Table 3. SAR of N(1)-Aryl Fragments.
a
Measured at [Tracer] ≈ Kd[Tracer].
b
Measured at [ATP] ≈ Km[ATP].
c
Selectivity expressed as the ratio of JAK1, JAK2, or CDK2 IC50 over HPK1 IC50.
d
See ref (19).
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