Skip to main content
. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Nat Metab. 2020 Oct 26;2(11):1232–1247. doi: 10.1038/s42255-020-00296-1

Fig. 5: Ketogenic diet enhances cardiac fatty acid metabolism.

Fig. 5:

a, Heatmap of acylcarnitine species measured in hearts of low fat (LF)- or ketogenic diet (KD)-fed fl/fl or CS-Mpc2−/− mice (n=6). b-d, Concentrations of free carnitine, total acylcarnitines, and the acylcarnitine/free carnitine ratio measured by mass-spectrometry of heart tissue (n=6). e-l, Gene expression markers of PPARα and fatty acid oxidation (Ppara, Ppargc1a, Pdk4, Acox1, Acot1, Acsl1, Cpt1b, and Hmgcs2) from heart tissue of LF- or KD-fed mice (n=7, 5, 6, and 6 for fl/fl LF, CS-Mpc2−/− LF, fl/fl KD, and CS-Mpc2−/− KD, respectively). Mean ± s.e.m. shown within dot plot. Each symbol represents an individual sample. Two-way ANOVA with Tukey’s multiple-comparisons test.