Table 3.
Univariate and multivariate analysis of prognostic factors in GC patients
| Factors | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| Cases | 5‐YSR | p‐value | HR | 95% CI | p‐value | |
| Sex | ||||||
| Male | 183 | 71.7% | 0.557 | 1.129 | 0.719–1.773 | 0.597 |
| Female | 65 | 57.7% | ||||
| Age (years) | ||||||
| ≤60 | 134 | 68.5% | 0.617 | 0.820 | 0.207–1.112 | 0.831 |
| >60 | 114 | 49.7% | ||||
| Tumor size | ||||||
| ≤5 cm | 182 | 70.3% | <0.001 | 1.447 | 0.886–2.363 | 0.139 |
| >5 cm | 66 | 30.3% | ||||
| pT stage | ||||||
| T1–T2 | 74 | 91.7% | <0.001 | 3.810 | 1.877–7.732 | <0.001 |
| T3–T4 | 174 | 46.3% | ||||
| pN stage | ||||||
| N0 | 91 | 83.6% | <0.001 | 2.880 | 1.631–5.084 | <0.001 |
| N1–3 | 157 | 44.4% | ||||
| M stage | ||||||
| M0 | 239 | 62.0% | <0.001 | 4.282 | 1.880–9.753 | <0.001 |
| M1 | 9 | 0.0% | ||||
| TNM stage | ||||||
| I–II | 117 | 63.9% | <0.001 | 2.775 | 1.466–5.255 | <0.001 |
| III–IV | 131 | 25.7% | ||||
| METTL14 expression | ||||||
| Low | 51 | 25.5% | <0.001 | 0.463 | 0.305–0.704 | <0.001 |
| High | 197 | 69.9% | ||||
Abbreviations: 5‐YSR, 5‐year survival rate; CI, confidence interval; GC, gastric cancer; HR, hazard ratio.