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. 2021 Jan 12;35(3):e23696. doi: 10.1002/jcla.23696

TABLE 4.

Comparison of the detection of PD‐L1 expression in large and small tissue specimens between the E1L3N and 22C3 assays

Large (n = 185) Small (n = 114) p value
E1L3N
Negative 125 (67.6%) 68 (59.6%)
Weak positive 40 (21.6%) 25 (21.9%) 0.160
Positive 20 (10.8%) 21 (18.4%)
22C3
Negative 127 (68.6%) 66 (57.9%)
Weak positive 38 (20.5%) 26 (22.8%) 0.080
Positive 20 (10.8%) 22 (19.3%)
Overall agreement 97.8% (94.6–99.4%) a 93.9% (87.8–97.5%) 0.076
a

95% confidence interval.