Table 3.
Outcome according to reperfusion.
| Cardioembolic group | Successful reperfusion
group n = 520 |
Unsuccessful reperfusion group*
n = 131 |
p-value† | Odds ratio† (95% CI) | p-value shift analysis |
|---|---|---|---|---|---|
| mRS at 3 months | <0.0001‡ | ||||
| 0–1 | 106 (20.4%) | 21 (16.2%) | 0.278 | 1.33 (0.80–2.22) | |
| 0–2 | 228 (43.8%) | 36 (27.7%) | 0.001 | 2.04 (1.34–3.11) | |
| 0–5 (survival) | 393 (75.6%) | 80 (61.1%) | 0.001 | 1.97 (1.32–2.96) | |
| Median, range | 3, 0–6 | 4, 0–6 | <0.0001 | ||
| Updated Charlson Comorbidity Index | <0.0001‡ | ||||
| Median, range | 2, 0–16 | 4, 0–13 | <0.0001 | ||
| Subitem heart failure | 162 (31.2%) | 52 (40%) | 0.056 | 0.70 (0.46–1.01) | |
| Symptomatic intracranial haemorrhage | 24 (4.5%) | 7 (5.2%) | 0.707 | 0.85 (0.36–2.01) | NA |
| Large-artery atherosclerosis group (all patients) | Successful reperfusion
group n = 126 |
Futile reperfusion group*
n = 41 |
p-value† | Odds ratio† (95% CI) | p-value shift analysis |
| mRS at 3 months | 0.083‡ | ||||
| 0–1 | 25 (20.8%) | 4 (9.8%) | 0.120 | 2.43 (0.79–7.47) | |
| 0–2 | 63 (52.5%) | 15 (36.6%) | 0.081 | 1.92 (0.92–3.97) | |
| 0–5 (survival) | 102 (85%) | 33 (80.5%) | 0.499 | 1.37 (0.55–3.45) | |
| Median, range | 2, 0–6 | 3, 0–6 | 0.093 | ||
| Updated Charlson Comorbidity Index | 0.503‡ | ||||
| Median, range | 2, 0–12 | 4, 0–9 | 0.534 | ||
| Subitem heart failure | 21 (17.5%) | 9 (22%) | 0.528 | 0.75 (0.31–1.81) | |
| Symptomatic intracranial haemorrhage | 7 (5.6%) | 2 (4.9%) | 0.868 | 1.15 (0.23–5.75) | NA |
| Large-artery atherosclerosis group (high-grade stenosis patients only) | Successful reperfusion
group n = 65 |
Futile reperfusion group*
n = 24 |
p-value† | Odds ratio† (95% CI) | p-value shift analysis |
| mRS at 3 months | 0.523‡ | ||||
| 0–1 | 14 (21.5%) | 3 (12.5%) | 0.342 | 1.92 (0.50–7.39) | |
| 0–2 | 29 (44.6%) | 11 (45.8%) | 0.918 | 0.95 (0.37–2.44) | |
| 0–5 (survival) | 56 (86.2%) | 19 (79.2%) | 0.422 | 1.64 (0.49–5.50) | |
| Median, range | 3, 0–6 | 3, 0–6 | 0.766 | ||
| Updated Charlson Comorbidity Index | 0.806‡ | ||||
| Median, range | 2, 0–12 | 2, 0–9 | 0.826 | ||
| Subitem heart failure | 10 (15.4%) | 5 (20.8%) | 0.544 | 0.69 (0.21–2.28) | |
| Symptomatic intracranial haemorrhage | 4 (5.8%) | 1 (4%) | 0.733 | 1.48 (0.16–13.88) | NA |
Values are presented as number (%). Percentages indicate available data. Missing data were considered as missing, as they were incidentally missing.
*
Denominator.
†
Values compare both groups.
‡
Shift over the whole spectrum of the score.
CI, confidence interval; mRS, Modified Rankin scale; NA, not applicable.