Table 4.

Fabrication of fibrous scaffolds: advantages and disadvantages.

Method	Advantages	Disadvantages	References
Fiber Mesh	High surface area for cell attachment	Low structural stability	[21]
Fiber Bonding	High surface to volume ratio, high porosity	Limited applications to other polymers	[132]
Electrospinning	Induces cell alignment and directionality	Limited by cell seeding	[143,144,145]
Phase Separation	No reduction in the activity of molecules	Difficult to control the scaffold morphology	[138,146]
Self-Assembly	Form extremely stable scaffolds, less use of organic solvent	Expensive material, complicated and elaborate process	[147,148]