Fig. 2.

Age-related differences in plasma proteins. a Exploratory analysis with samples marked based on age, visualized with Principal Component Analysis (PCA) of proteins in plasma prepared from umbilical cord blood and venous blood collected at 1 month, 4 months, 18 months, 36 months and 8 years of age. b Volcano plot depicting protein associations with the two age-related clusters in the PCA analysis with the 10 most different proteins marked by name. Red colour represents significant associations with a Bonferroni corrected P-value < 0.05. c Exploratory analysis with samples marked based on allergy development or not, visualized with Principal Component Analysis (PCA) with plasma prepared from umbilical cord blood and venous blood collected at 1 month, 4 months, 18 months, 36 months and 8 years of age