Fig. 1.
Activity of Mpro. (A) The structures of three substrates. (B) Activity of 50 nM Mpro on 10 μM Sub1. (C) Activity of 50 nM Mpro on 10 μM Sub2 and Sub3. The florescence signals are normalized for easy comparison. (D) Activity of different concentrations of Mpro on 10 μM Sub3 plotted as fluorescence intenisty (fluo. int.) in arbitrary units (a.u.) vs time graph. All experiments were carried with three repeats, and data are presented as the average of three repeats in color, with error bars shown in black.