Table 2.

Fungi-derived compounds and their functions

Fungi-derived compounds		Functions	References
Quorum-sensing molecules	Farnesol	Filamentous growth and formation ↓ C. albicans biofilm formation ↓	[85–91]
		Drug-resistance ↓ Synergy with fluconazole, amphotericin B or micafungin, anti-fungal AMP peptidomimetics, chitosan (CS), and cysteine protease metacaspase
	Tyrosol	C. albicans biofilm formation ↓
Fungal secondary metabolites		Source of antibiotics and immunosuppressant drugs Hepatotoxicity and/or nephrotoxicity	[54, 92, 93]
Fungi-derived extractives	(1,3)/(1,6)-β-glucan	Obesity property ↓	[94–97]
	Pyronepolyene C-glucoside iso-D8646-2-6	Influenza A virus (H1N1) infection ↓
	Xanthones	Virus infection (H1N1, simplex virus types 1 and 2) ↓
	Some mangrove-associated or soil-associated fungus-derived compounds	Virus infection ↓
Other compounds	Candidalysin	Systematic infection ↑ Phagocytic clearance ↓ Severity of ethanol-associated hepatitis ↑	[98–110]
	Prostaglandins E2 (PGE2)	Biofilm formation ↑ Yeast to hyphae transition ↑ C. albicans clearance by phagocytes ↓
	Oxylipins	Modulating immune responses

“↑” indicates increase and “↓” indicates decrease