Figure 2.

Effect of all active therapies on the rate of decline in FEV₁. The center of the diamond indicates the point estimate and the width is the 95% CI. BRONCUS = Bronchitis Randomized on NAC Cost-Utility Study; CI = confidence interval; COPD = chronic obstructive pulmonary disease; ISOLDE = Inhaled Steroids in Obstructive Lung Disease in Europe; LHS = Lung Health Study; LHS2 = Lung Health Study 2; SUMMIT = Study to Understand Mortality and Morbidity; TORCH = Toward a Revolution in COPD Health; UPLIFT = Understanding Potential Long-Term Impacts on Function with Tiotropium.