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. 2021 Jan 23;9(3):1603–1613. doi: 10.1002/fsn3.2134

TABLE 1.

Oxidative stress biomarkers in liver, gastrocnemius, and serum of rats fed the standard chow or HFD for 8, 14, and 20 weeks

Diet type Week8 Week14 Week20
Con OP OR Con OP OR Con OP OR
Liver
T‐AOC (U/mg prot) 0.88 ± 0.06 0.76 ± 0.12* 0.81 ± 0.06 0.90 ± 0.15 0.75 ± 0.14* 1.01 ± 0.18# 0.71 ± 0.10 0.55 ± 0.07 0.67 ± 0.10#
MDA (U/mg prot) 2.14 ± 0.51 2.76 ± 0.20* 2.43 ± 0.53# 2.02 ± 0.11 3.37 ± 0.33* 2.25 ± 0.37# 2.02 ± 0.39 4.25 ± 0.39* 2.27 ± 0.48#
GSH/GSSG 3.19 ± 0.28 2.99 ± 0.22 3.54 ± 0.35 2.38 ± 0.24 2.18 ± 0.12 3.31 ± 0.18*# 2.62 ± 0.32 1.91 ± 0.07* 2.27 ± 0.19
ROS (103AUC/μl) 1.01 ± 0.06 1.52 ± 0.63* 0.77 ± 0.18*# 1.03 ± 0.06 1.53 ± 0.38* 1.30 ± 0.25 1.02 ± 0.21 1.89 ± 0.74* 1.74 ± 0.95*
Gastrocnemius
T‐AOC (U/mg prot) 0.27 ± 0.04 0.25 ± 0.03 0.38 ± 0.06*# 0.37 ± 0.08 0.28 ± 0.07* 0.47 ± 0.03# 1.10 ± 0.08 0.76 ± 0.03* 1.02 ± 0.05
MDA (U/mg prot) 1.78 ± 0.22 2.58 ± 0.31* 1.79 ± 0.44# 3.94 ± 0.64 4.83 ± 0.69* 3.56 ± 0.82# 2.72 ± 0.51 3.93 ± 0.51* 3.22 ± 0.13#
GSH/GSSG 4.66 ± 0.4 4.02 ± 0.24* 4.45 ± 0.21# 4.61 ± 0.29 4.65 ± 0.25 4.76 ± 0.34 6.45 ± 0.24 5.74 ± 0.12* 6.02 ± 0.06
ROS (103AUC/ul) 1.03 ± 0.13 1.13 ± 0.18 0.90 ± 0.11# 1.01 ± 0.29 1.27 ± 0.19* 1.09 ± 0.25 1.01 ± 0.14 1.35 ± 0.08* 1.28 ± 0.07*
Serum
T‐AOC (U/mg prot) 5.33 ± 0.34 4.49 ± 0.23* 4.79 ± 0.24 5.60 ± 0.21 5.04 ± 0.35* 5.68 ± 0.14# 5.44 ± 0.19 4.14 ± 0.20* 5.18 ± 0.37#
MDA (U/mg prot) 4.90 ± 0.41 6.12 ± 0.38* 5.44 ± 0.57 4.90 ± 0.51 6.35 ± 0.56* 6.25 ± 0.29* 2.56 ± 0.54 4.17 ± 0.35* 3.15 ± 0.42#
GSH/GSSG 7.58 ± 0.14 4.07 ± 0.16* 6.49 ± 0.20# 7.56 ± 0.34 5.46 ± 0.24* 7.47 ± 0.31# 7.12 ± 0.29 5.43 ± 0.14* 6.89 ± 0.11#
ROS (103AUC/μl) 1.02 ± 0.14 1.27 ± 0.22* 1.06 ± 0.25 1.10 ± 0.16 1.30 ± 0.24* 1.25 ± 0.32 1.00 ± 0.28 1.45 ± 0.37* 1.16 ± 0.35#

Data were presented as mean ± SEM. Con, control group; OP, obesity‐prone; OR, obesity‐resistant. * p < .05 versus Con; # p < .05 versus OP.