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Global observation of dysregulated genes in HCC cells with CDCA8 depletion. (A) The number of genes dysregulated in Huh1 and/or Huh7 cells over 48 h of CDCA8-1siRNA treatment. (B) A heat map of the 50 commonly up- or downregulated genes in Huh1 and Huh7 cells. p < 0.001, red (upregulated) and green (downregulated). (C,D) Two putative ingenuity pathway analysis (IPA) top networks highly associated with PCNA (C) or ATF3 (D).
