FIGURE 2.
The mechanism of UBA1 inhibition by TAK-243. The steps involved in the activation of ubiquitin by UBA1 are shown as well as the mode of action of TAK-243 as described in the main text. The black circle indicates a non-covalent association.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.