Table 1.
Anthropometric, clinical characteristics, in-hospital treatments, and outcomes of patients included in the final analysis.
| Covid-19 Patients (n= 20) |
||
|---|---|---|
| Age at admission, years | 58.2 (15.5) | |
| Males, n (%) | 14 (70) | |
| BMI, kg/m2 | 27.6 (5.7) | |
| Ex and active smokers, n (%) | 4 (20%) | |
| Arterial hypertension, n (%) | 11 (55) | |
| Diabetes mellitus, n (%) | 2 (10) | |
| Ischaemic heart disease, n (%) | 2 (10) | |
| Chronic treatments | ||
| Angiotensin receptor blockers, n (%) | 5 (20) | |
| ACE inhibitors, n (%) | 2 (10) | |
| Blood count & Biochemistry at admission | ||
| Lymphocytes < 1500 × 109/µL, n (%) | 14 (70) | |
| D-dimer, mg/L FEU | 768 (374–3966) | |
| D-dimer ≥ 1000 mg/L FEU, n (%) | 9 (45) | |
| Gas exchange at admission | ||
| pH | 7.45 (0.03) | |
| PaCO2, mmHg | 42 (35–49) | |
| PaO2/FiO2, mmHg | 264 (128) | |
| PaO2/FiO2 | <100 mmHg, n (%) | 2 (10) |
| 100–200 mmHg, n (%) | 6 (30) | |
| 201–300 mmHg, n (%) | 4 (20) | |
| >300 mmHg, n (%) | 8 (40) | |
| A-a O2 gradient, mmHg | 144 (17–253) | |
| A-a O2 gradient >200 mmHg, n (%) | 8 (40) | |
| In-hospital treatments | ||
| Systemic methylprednisolone, n (%) | 15 (75) | |
| LMWH, prophylaxis, n (%) | 11 (55) | |
| LMWH, anticoagulant, n (%) | 9 (45) | |
| CPAP, n (%) | 13 (65) | |
| CPAP duration, days | 10.9 (3.5) | |
| Outcomes | ||
| From symptoms onset to 1st PFT, days | 28.2 (13.5) | |
| From admission to 1st PFT, days | 9.1 (6.3) | |
| From discharge to 2nd PFT, days | 43.8 (5.7) | |
| From 1st to 2nd PFT, days | 52.4 (6.4) | |
| Hospital stay duration, days | 18.2 (11.7) | |
| Treatments at discharge | ||
| O2 therapy, n (%) | 4 (20) | |
| LMWH, n (%) | 12 (60) | |
Data are reported as means (standard deviation, SD), medians (inter-quartile range, IQR) and frequencies. BMI = body mass index; LMWH = low molecular weight heparin; PFT = pulmonary function test; CPAP = continuous positive airway pressure; PEEP = positive end expiratory pressure; A-a O2 gradient = alveolar arterial oxygen gradient; PaO2/FiO2 = arterial partial oxygen pressure to fraction of inspired oxygen ratio; PaCO2 = arterial partial carbon dioxide pressure; INR = international normalized ratio; FEU = fibrinogen equivalent unit.