Table 3.
Clinical characteristics during hospitalization in patients with DLco ≥80% predicted and DLco < 80% predicted.
| DLco < 80% Predicted (n = 13) |
DLco ≥ 80% Predicted (n = 7) |
p-Value | ||
|---|---|---|---|---|
| Age, years | 58.5 (14.6) | 57.7 (18.3) | 0.921 | |
| BMI, Kg/m2 | 24.9 (23.3–27.2) | 31.1 (22.7–33.0) | 0.311 | |
| Males, n (%) | 9 (69) | 5 (71) | 0.664 | |
| Arterial hypertension, n (%) | 7 (54) | 4 (57) | 0.630 | |
| Diabetes mellitus, n (%) | 2 (15) | 0 (0) | 0.411 | |
| Ischemic heart disease, n (%) | 1 (8) | 1 (14) | 0.589 | |
| Biochemistry at admission | ||||
| White blood cells × 109/µL | 9420 (5010–14,515) | 5890 (4560–7720) | 0.347 | |
| D-dimer, mg/L FEU | 3375 (607–5699) | 394 (200–733) | 0.008 | |
| D-dimer > 1000 mg/L FEU, n (%) | 9 (69) | 0 (0) | 0.004 | |
| INR | 1.25 (1.13–1.42) | 1.17 (1.10–1.27) | 0.516 | |
| Lymphocytes × 109/µL | 1194 (590) | 1311 (726) | 0.701 | |
| Lymphocytes, % | 15.3 (9.9) | 24.3 (15.3) | 0.125 | |
| LDH, U/L | 370 (151) | 271 (127) | 0.161 | |
| Interventions during hospitalization | ||||
| CPAP, n (%) | 10 (77) | 3 (43) | 0.151 | |
| PEEP, mean (SD) | 10.2 (1.5) | 10.0 (2.5) | 0.869 | |
| CPAP days, mean (SD) | 11 (4) | 11 (3) | 0.957 | |
| LMWH, n (%) | 13 (100) | 6 (86) | 0.350 | |
| LMWH, n (%) | Treatment | 6 (46) | 5 (71) | 0.272 |
| Prophylaxis | 7 (54) | 1 (14) | 0.106 | |
| Corticosteroids, n (%) | 10 (77) | 5 (71) | 0.594 | |
Data are expressed as means (SD), median (IQR) and frequencies, as appropriate. Significant differences are in bold. BMI = body mass index; LMWH = low molecular weight heparin; CPAP = continuous positive airway pressure; PEEP = positive end expiratory pressure; INR = international normalized ratio; FEU = fibrinogen equivalent unit.