Table 5.
Unstandardized Coefficient | Standardized Coefficient | 95% CI | p-Value | |
---|---|---|---|---|
Model 1 (adj R2: 0.786) |
||||
FEV1 %pred | −0.043 | −0.050 | −0.442–0.355 | 0.820 |
VC %pred | 0.227 | 0.235 | −0.294–0.748 | 0.368 |
TSS, points | −0.623 | −0.155 | −1.877–0.632 | 0.307 |
Lg10 D-dimer | −18.675 | −0.655 | −28.373– −9.076 | 0.001 |
Model 2 (adj R2: 0.786) |
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FEV1 %pred | −0.026 | −0.030 | −0.426–0.373 | 0.868 |
VC %pred | 0.161 | 0.167 | −0.374–0.697 | 0.172 |
TSS, points | −0.426 | −0.106 | −1.710–0.859 | 0.209 |
D-dimer ≥ 1000 FEU | −22.849 | −0.716 | −34.594– −11.105 | 0.001 |
Multiple regression analysis models for predicting DLco % predicted at follow up. Having a D-dimer > 1000 at admission is associated with a DLco reduction of 22% at 6 weeks post-discharge. Variables significantly different at the univariate analysis (FEV1, VC, TSS, and D-dimer) were used for the linear regression analysis. FVC was excluded from the model because it is intrinsically highly correlated with VC (see legend of Figure 4 for details). CI = confidence interval; FEV1 = forced expiratory volume in one second; VC = vital capacity; TSS = total severity score