Table 1.
Impact of Resistance-Associated Mutations on the Genotypic Sensitivity Score
| Threshold of Virus Variants | Samples With RAMs for NRTIs and NNRTIs | Samples With Rilpivirine Resistance According to ANRS Algorithm | Samples With Rilpivirine Resistance According to Stanford Algorithm | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotypic Sensitivity Score According to ANRS | Genotypic Sensitivity Score According to Stanford | ||||||||||||
| GSS = 0 | GSS = 1 | GSS = 2 | GSS = 2.5 | GSS = 3 | GSS = 0 | GSS = 1.5 | GSS = 2 | GSS = 2.5 | GSS = 3 | ||||
| 20% | 142 | 13 | 9 | 0 | 0 | 8 | 5 | 128 | 0 | 0 | 0 | 10 | 132 |
| 5% | 165 | 18 | 16 | 0 | 1 | 13 | 5 | 146 | 0 | 1 | 3 | 14 | 147 |
| 1% | 229 | 43 | 36 | 1 | 4 | 48 | 5 | 171 | 0 | 2 | 13 | 33 | 181 |
Abbreviations: ANRS, French National Agency for Research on AIDS and Viral Hepatitis; GSS, genotypic sensitivity score; NNRTI, nonnucleoside reverse transcriptase inhibitor; NRTI, nucleos(t)ide reverse transcriptase inhibitor; RAM, resistance-associated mutation.