Table 1.

Cancer subtypes and other clinical pathologies associated with Shoc2 and Erbin.

Protein	Associated Pathologies	Key reference
SHOC2	Noonan-like syndrome with loose anagen hair	[44]
	Breast cancer	[60]
	Colorectal cancer	[31]
	Non-small-cell lung cancer	[22]
	Pancreatic cancer	[37]
ERBIN	Atopy	[101]
	Cardiac hypertrophy	[79]
	Diabetic peripheral neuropathy	[80]
	Inflammatory bowel disease (Crohn’s disease)	[105]
	Renal interstitial fibrosis	[104]
	Striate palmoplantar keratoderma	[86]
	Acute myeloid leukemia	[119]
	Breast cancer	[126]
	Cervical cancer	[110]
	Colorectal cancer	[95]
	Head and neck squamous cell cancer	[115]
	Hepatocellular carcinoma	[123]