Table I.
Clinical and demographic characteristics of small cell lung cancer patients
| Parameter | Value |
|---|---|
| Gender, n (%): | |
| Male | 65 (63) |
| Female | 38 (37) |
| Age: | |
| Age median ± SD [years]: | 64 ±7.5 |
| ≥ 64, n (%) | 48 (46.6) |
| < 64, n (%) | 55 (53.4) |
| Environmental/occupational exposure to carcinogens, n (%): | |
| Yes | 34 (33) |
| No | 69 (67) |
| Smoking status, n (%): | |
| Current smokers | 9 (8.7) |
| Former smokers | 89 (86.4) |
| Non-smokers | 4 (4.9) |
| Smoking intensity, n (%): | |
| Light smoker (< 15 pack-years) | 23 (23) |
| Heavy smoker (> 15 pack-years) | 77 (77) |
| Performance status, n (%): | |
| 0 | 25 (24.3) |
| 1 | 51 (49.5) |
| 2 | 27 (26.2) |
| 3 | 0 (0) |
| TNM, n (%): | |
| I | 3 (2.9) |
| II | 11 (10.7) |
| III | 30 (29.1) |
| IV | 59 (57.3) |
| Distant metastases, n (%): | |
| Yes | 63 (61.1) |
| No | 40 (38.9) |
| Response to platinum-based chemotherapy, n (%): | |
| PD | 12 (11.7) |
| SD | 53 (51.5) |
| PR | 37 (35.9) |
| CR | 1 (0.9) |
| Weight loss during chemotherapy (any grade), n (%): | |
| Yes | 27 (26.2) |
| No | 76 (73.8) |
| Neutropenia during chemotherapy (any grade), n (%): | |
| Yes | 55 (53.4) |
| No | 48 (46.6) |
| Anaemia during chemotherapy (any grade), n (%): | |
| Yes | 52 (50.5) |
| No | 51 (49.5) |
| Radiotherapy, n (%): | |
| Yes | 58 (56.3) |
| No | 45 (43.7) |
| Treatment regimen: | |
| Cisplatin + etoposide | 101 (98) |
| Carboplatin + etoposide | 2 (2) |
| Chemotherapy (no. of cycles): | |
| 1 | 4 (3.9) |
| 2 | 9 (8.7) |
| 3 | 4 (3.9) |
| 4 | 21 (20.4) |
| 5 | 13 (12.6) |
| 6 | 52 (50.5) |
PD – progression of disease, SD – stable disease, PR – partial remission, CR – complete remission.