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. Author manuscript; available in PMC: 2021 Mar 15.
Published in final edited form as: Mol Cell. 2020 Nov 19;81(1):139–152.e10. doi: 10.1016/j.molcel.2020.10.035

Figure 7. Two roles of MglA-SspA in Ft virulence activation.

Figure 7.

Schematic model for Ft virulence gene activation. Upper, PigR-independent genes are activated by MglA-SspA stabilizing σ70 and DNA interactions with FtRNAP. Lower, PigR-dependent genes involve PigR binding to (MglA-SspA)-ppGpp to recruit αCTDs to UP elements.