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. Author manuscript; available in PMC: 2022 Mar 16.
Published in final edited form as: J Am Coll Cardiol. 2021 Mar 16;77(10):1302–1312. doi: 10.1016/j.jacc.2021.01.018

Figure 1. Multivariable adjusted hazard ratios (HRs) and 95% confidence intervals (CI) for cause-specific premature mortality (before age 70 y) according to the occurrence of HDPs among 88,395 parous women (NHS-II, 1989–2017).

Figure 1.

In the age-adjusted model, age in months at the start of follow-up and calendar year of the current questionnaire cycle was included as a stratified variable. Multivariable model 1 was further adjusted for White race/ethnicity, pre-pregnancy BMI, and time-varying menopausal status, current hormone therapy use, daily aspirin use, and parental history of MI or stroke. Multivariable model 2 was further adjusted for time-varying breastfeeding duration, parity, alcohol intake, smoking status, physical activity, AHEI-2010 dietary score, and current BMI. HDPs= Hypertensive disorders of pregnancy; GHTN=gestational hypertension; PY= person year; CI = Confidence intervals. The associations of GHTN and pre-eclampsia with premature mortality were assessed separately and always against normotensive pregnancies.