Table 3:

Head dip (HD) and stretched attend posture (SAP) counts in the elevated plus maze

Group	Male HINT1 +/+	Male HINT1 −/−	Female HINT +/+	Female HINT1 −/−
Saline	HD: 2.8 ± 0.7	HD: 4.0 ± 1.2	HD: 4.1 ± 1.4	HD: 2.4 ± 0.6
	SAP: 0.3 ± 0.2	SAP: 0.5 ± 0.3	SAP: 0.7 ± 0.3	SAP: 0.5 ± 0.3
0.025 mg/kg, nic	HD: 3.8 ± 0.8	HD: 3.2 ± 1.4	HD: 4.0 ± 0.7	HD: 4.3 ± 1.3
	SAP: 0.3 ± 0.2	SAP: 0.5 ± 0.2	SAP: 0.3 ± 0.2	SAP: 0.5 ± 0.3
0.05 mg/kg, nic	HD: 8.3 ± 1.4*,**	HD: 1.8 ± 0.7	HD: 5.3 ±2.0	HD: 3.8 ± 1.2
	SAP: 0.2 ± 0.2	SAP: 0.2 ± 0.2	SAP: 0.3 ± 0.2	SAP: 0.2 ± 0.2
0.1 mg/kg, nic	HD: 7.1 ± 1.9*,**	HD: 0.4 ± 0.2	HD: 0.8 ± 0.4***	HD: 0.5 ± 0.3***
	SAP: 0.3 ± 0.2	SAP: 0.2 ± 0.2	SAP: 0.5 ± 0.2	SAP: 0.3 ± 0.2

Each point represents the mean ± SEM of six mice per group. nic, nicotine.

^*Denotes P < 0.05 vs. corresponding saline group;

^**Denotes P < 0.05 vs. corresponding HINT1 −/− group;

^***Denotes P < 0.05 vs. all other groups.