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. 2021 Mar 11;13:2295–2306. doi: 10.2147/CMAR.S281377

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© 2021 Yu et al.

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Circ_0005927 expression was dramatically downregulated in CRC tissues and cells and was correlated with poor clinical outcome. (A and B) GSE142837 microarray dataset and qRT-PCR showed that circ_0005927 expression was lower in CRC tissues than that in healthy intestinal tissues. (C and D) Circ_0005927 expression was detected by qRT-PCR in CRC tissues, normal intestinal tissues, NCM460 cells, SW620 cells, SW480 cells, Caco-2 cells and LoVo cells. (E and F) RNase R treatment assay was employed to demonstrate that circ_0005927 was more stable than linear GAPDH. *P<0.05 and **P<0.01.