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. 2021 Mar 11;13:2295–2306. doi: 10.2147/CMAR.S281377

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© 2021 Yu et al.

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Circ_0005927 overexpression repressed CRC cell processes by regulating miR-942-5p and BATF2. (A) Western blot was used to determine the knockdown efficiency of si-BATF2 in LoVo and SW620 cells. (B) The effects between circ_0005927 and miR-942-5p mimic or BATF2 silencing on cell colony-forming ability were revealed by cell colony formation assay in LoVo and SW620 cells. (C) Flow cytometry analysis was performed to investigate the impacts between circ_0005927 overexpression and miR-942-5p mimic or BATF2 depletion on cell apoptosis in LoVo and SW620 cells. (D and E) Transwell assay was employed to display the influences between circ_0005927 and miR-942-5p mimic or BATF2 absence on the migration and invasion of LoVo and SW620 cells. **P<0.01.