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. 2021 Mar 3;15(3):e0009183. doi: 10.1371/journal.pntd.0009183

Fig 5. FAMP-reduced neurogenesis deficits caused by ZIKV infection.

Fig 5

(A) The in vitro system to study the effects of FAMP on K048? hNS/PCs after ZIKV infection. (B) Gene transcription levels were measured by RT-qPCR. Data are presented as mean ± SD (n = 4), * p<0.05, ** p<0.01, **** p<0.0001, two-way ANOVA with a Dunnett’s multiple comparisons test. (C) Newly generated neurons were stained by Tuj1 (red). Blue, nuclear counterstain. Scale bars: 40 μm. (D) Quantification data are presented as mean ± SD (n = 4), ** p<0.01, **** p<0.0001, one-way ANOVA with a Tukey post hoc test. (E) ZIKV RNA loads in the culture medium collected on Days 1, 2, 6, 9 and 12 were measured by RT-qPCR. Data are presented as mean ± SD (n = 3).