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. 2020 Oct 19;117(44):27516–27527. doi: 10.1073/pnas.2002817117

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Fig. 1. — Divergent gut microbiome phenotypes in wild-derived PWD mice and classic inbred B6 mice. Comparison of gut microbial composition in PWD and B6 mice. Distribution of phyla (A) and genera (B) comprising bacterial 16S reads. Each bar represents an individual mouse. (C) β-Diversity analysis of B6 and PWD fecal microbiomes assessed using unweighted UniFrac distance. (D) α-Diversity analysis of B6 and PWD fecal, assessed using Chao1, Shannon index, or phylogenetic distance. (E) DNA from fecal and cecal samples was isolated from the same individual mice and analyzed by 16S sequencing using unweighted UniFrac distance. Samples from individual mice of each strain are designated by numbering with a total of 32 B6 (17 female and 15 male) and 19 PWD (10 female and 9 male) mice with all 16S data rarefied to 7,000 reads.