Table 1.
Baseline characteristics of white participants according to WHRonly+ PGS in the POUNDS Lost Trial
| Characteristics | Tertiles of the WHRonly+ PGS | Pa | ||
|---|---|---|---|---|
| T1(n=192) | T2(n=193) | T3(n=198) | ||
| Age, y | 51.7±9.1 | 52.6±8.7 | 52.0±9.1 | 0.75 |
| Female, n (%) | 104(54.2) | 108(56.0) | 116(58.6) | 0.68 |
| Height, cm | 170.2±8.9 | 169.5±8.8 | 168.2±8.7 | 0.03 |
| Weight, kg | 93.7±15.6 | 94.9±15.6 | 92.4±16.6 | 0.75 |
| BMI, kg/m2 | 32.2±3.9 | 32.9±4.0 | 32.5±3.9 | 0.43 |
| Waist, cm | 104.1±12.6 | 105±13.6 | 103.7±14.1 | 0.78 |
| Glucose, mg/dL | 90.5±10.1 | 91.9±10.6 | 94.7±14.1 | 0.0002 |
| Insulin, μU/mL | 9.5(6.4, 14.0) | 10.5(7.1, 15.3) | 10.9(7.3, 16.4) | 0.04 |
| HOMA-IR | 2.1(1.4, 3.1) | 2.4(1.5,3.5) | 2.5(1.6, 3.9) | 0.01 |
| HOMA-B | 127.2(96.4, 186.9) | 130.3(103.2, 186.4) | 131.5(87.5, 201.2) | 0.75 |
| HbAlc, % | 5.3±0.3 | 5.4±0.4 | 5.4±0.4 | 0.16 |
| Diet group, n (%) | 0.36 | |||
| High fat, high protein | 53(27.6) | 54(28.0) | 37(18.7) | |
| High fat, average protein | 49(25.5) | 44(22.8) | 58(29.3) | |
| Low fat, high protein | 44(22.9) | 48(24.9) | 51(25.8) | |
| Low fat, average protein | 46(24.0) | 47(24.4) | 52(26.3) | |
| Dietary intake per day2 | ||||
| Energy, kcal | 2005±607 | 1992±522 | 1958±523 | 0.79 |
| Carbohydrate, % of energy | 43.4±8.0 | 44.9±7.5 | 44.3±7.7 | 0.55 |
| Fat, % of energy | 37.5±6.4 | 36.9±6.1 | 37.0±5.7 | 0.62 |
| Protein, % of energy | 18.7±3.5 | 17.7±3.1 | 18.3±3.6 | 0.45 |
| Biomarkers of adherence | ||||
| Respiratory quotient | 0.84±0.04 | 0.84±0.04 | 0.84±0.04 | 0.52 |
| Urinary nitrogen, g/d | 12.6±4.0 | 12.4±4.2 | 12.6±5.3 | 0.56 |
Values are means±SDs, median (25th, 75th), or n (%). Insulin, HOMA-IR, HOMA-B were log-transformed before analysis.
a
P values were calculated by using the chi-square test for categorical variables and general linear regression test after adjusting for age (except age) and sex for continuous variables.