Table 3. The top hit@10 results (partial and free settings) for relation prediction of our biological knowledge graph as feature generators models.
Partial and free settings are two evaluation strategies correspond to: partially removing 80% of the relation edges and completely removing all relation edges, respectively.
Relation | Walking RDF/OWL | TransE | Poincaré | Rescal | SimplE | R-GCN |
---|---|---|---|---|---|---|
partial | ||||||
has function | 12.97 | 10.51 | 7.36 | 5.62 | 19.20 | 9.35 |
has interaction | 11.51 | 13.18 | 3.75 | 8.62 | 8.60 | 11.40 |
has disease annotation | 31.10 | 26.31 | 21.76 | 19.40 | 24.02 | 20.42 |
has sideeffect | 22.42 | 25.70 | 5.70 | 17.07 | 17.26 | 17.21 |
has indication | 26.09 | 18.40 | 9.77 | 13.09 | 14.66 | 11.83 |
has target | 15.32 | 13.70 | 7.68 | 5.50 | 20.28 | 10.93 |
has gene phenotype | 15.23 | 14.89 | 8.67 | 8.59 | 8.97 | 10.07 |
has disease phenotype | 34.69 | 19.86 | 11.36 | 10.32 | 8.61 | 7.22 |
free | ||||||
has function | 3.16 | 2.54 | 0.43 | 0.75 | 2.31 | 2.56 |
has interaction | 4.14 | 2.53 | 1.84 | 0.74 | 2.81 | 0.89 |
has disease annotation | 22.51 | 21.90 | 8.02 | 14.24 | 10.96 | 15.75 |
has sideeffect | 18.14 | 21.20 | 0.05 | 13.94 | 5.82 | 6.77 |
has indication | 14.78 | 11.95 | 5.25 | 9.61 | 9.09 | 13.40 |
has target | 0.24 | 0.26 | 0.06 | 0.12 | 1.73 | 0.63 |
has gene phenotype | 9.08 | 9.61 | 0.94 | 6.80 | 1.94 | 4.65 |
has disease phenotype | 10.83 | 4.73 | 1.10 | 3.05 | 1.59 | 1.89 |
Note:
The highest performing method is indicated in bold.