Table 3.
Tabulation of the proposed photon dose scheme and its calculated BEDα/β based on experimental values of α/β ratios and of oxygen enhancement ratio (OER) [Eqn. (3)].
| Dose schemes | Hypoxic condition | ||
|---|---|---|---|
| Physical dose | Number of | BEDα/β | |
| per fraction (Gy) | fractions | (Gy) | |
| 1. Conventional photon | 2 | 30 | 72 |
| 2. Hyperfractionated photon | 2.52 | 25 | 72 |
| 3. Hypofractionated photon | 5.6 | 10 | 74 |
Values of α/β = 10 Gy and OER = 1 were used in the conventional photon dose scheme (1), while α/β = 17.7 Gy and OER = 1.4 were applied to hyperfractionated (2) and hypofractionated (3) dose scheme. BED10 = 72 Gy is referred as the standard conventional radiotherapy dose scheme in the current study. Physical dose per fraction in hyperfractionated scheme of 1.8 Gy*1.4 = 2.52 Gy and in hypofractionated scheme of 4 Gy*1.4 = 5.6 Gy with α/β = 17.7 Gy were used to calculate the number of fractions with their corresponding BEDα/β close to 72 Gy to match the dose scheme with the standard reference dose scheme.