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. 2021 Feb 25;8:585691. doi: 10.3389/fcvm.2021.585691

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Copyright © 2021 Wang, Guo, Li, He, Zheng, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dynamic interaction between EZH2 and Malat1 locus-derived lncRNAs during AngII treatment. (A) Schematic diagram of the Malat1 genomic structure together with two antisense lncRNAs, Gm20417, and Gm37376. (B–D) Relative reads of Malat1 (B), Gm20417 (C) and Gm37376 (D) normalized to corresponding IgG groups. (E) Impact of Gm37376 and Gm20417 on H3K27me3 in MEFs. Cells were collected 24 h after transfection, and the lysates were immunoblotted with anti-H3K27me3 and anti-H3 antibodies. Data are mean ± SEM; n = 3.