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. 2021 Feb 24;12:607572. doi: 10.3389/fphar.2021.607572

FIGURE 3.

FIGURE 3

Sections of sciatic nerve processed for neurofilament immunohistochemistry. Treatments are indicated as follows: (A) SHAM SHR + saline solution; (B) CCI SHR + saline solution; (C) CCI SHR + (+/−)-thioctic acid 125 μmol·kg−1·die−1; (D) CCI SHR + (+/−)- thioctic acid 250 μmol·kg−1·die−1; (E) CCI SHR + (+)- thioctic acid 125 μmol·kg−1·die−1; (F) CCI SHR + (−)-thioctic acid 125 μmol·kg−1·die−1; (G) CCI SHR + pregabalin 300 μmol·kg−1·die−1. Left-bottom graph represents a densitometric analysis of the expression of neurofilament. Each experimental group is n = 6; data, expressed as Optical Density Unit (ODU), are the mean ± SEM. Calibration bar: 10 μm *p < 0.05 vs SHAM SHR, ^p < 0.05 vs CCI SHR + saline solution.