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. 2021 Feb 25;11:614093. doi: 10.3389/fonc.2021.614093

Table 3.

LM risk factors in all patients.

Exposure Univariable model HR (95% CI) p-value Multivariable model HR (95% CI) p-value
Age at diagnosis 0.99 (0.97, 1.00) 0.1458 1.01 (0.96, 1.05) 0.7963
Differentiation grade
 G1 1.0 1.0
 G2 3.33 (0.18, 61.68) 0.4187 0.00 (0.00, Inf) 0.9980
 G3 14.29 (1.41, 144.36) 0.0242* 83.01 (0.61, 11366.93) 0.0783
 G4 2.86 (0.24, 34.66) 0.4097 8.39 (0.13, 538.41) 0.3165
Laterality
 Unilateral 1.0 1.0
 Bilateral 1.69 (0.74, 3.86) 0.2155 1.43 (0.51, 3.97) 0.4939
Invasion
 Tis 1.0 1.0
 T1 10.50 (1.30, 84.88) 0.0274* inf. (0.00, Inf) 0.9959
 T2 8.75 (0.70, 108.79) 0.0916 inf. (0.00, Inf) 0.9959
 T3 inf. (0.00, Inf) 0.9910 inf. (0.00, Inf) 0.9948
 T4 inf. (0.00, Inf) 0.9962 inf. (0.00, Inf) 0.9974
 >T4 1.0 1.0
Tumor size
 <4 cm 1.0 1.0
 ≥4 cm 1.40 (0.46, 4.26) 0.5530 1.94 (0.46, 8.12) 0.3658

*Statistically significant.