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. 2021 Feb 25;11:609160. doi: 10.3389/fcimb.2021.609160

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Copyright © 2021 Yin, Liu, He and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential long-term memory of transposable element (TE) upregulation. (A) Expression of TE subfamilies in 8-cell (8C) embryos developed from normal mouse zygote injected with tsRNA derived from sperm of high-fat-diet (HFD) male. (B) Expression of TE subfamilies in adult islet developed from normal mouse zygote injected with tsRNA derived from sperm of HFD male. (C) Expression of LTR elements in 8C embryos developed from normal mouse zygote injected with tsRNA derived from sperm of HFD male. (D) Expression of LTR elements in adult islet developed from normal mouse zygote injected with tsRNA derived from sperm of HFD male. (E) Scheme of the process from obtaining tsRNA injected zygote to examining TE expression in 8C embryos and adult islet.