Table 1:
Neuroimaging parameters of the included studies
| Studies | Scanner/Technique/Field Strength | Gap/Raters |
|---|---|---|
| Benedictus et al, 201328 | GE Healthcare/EPI/3T | Unknown/1 neuroradiologist |
| Cordonnier et al, 20067 | Siemens/GRE/1T | 1.5/1 observer, type unknown |
| Fukui et al, 201321,a | Unknown/GRE/1.5T | Unknown |
| Goos et al, 201122,b | Siemens/GRE/1.5 | 1.5/1 rater, type unknown |
| Siemens/SWI/1.5T | NA/1 rater, type unknown | |
| Kester et al, 201429,a | GE Healthcare, Siemens/GRE/1T, 1.5T, and 3T | Unknown |
| Kirsch et al, 20094 | Siemens/SWI/1.5T | NA/4 readers +1 neuroradiologist |
| Nagasawa et al, 201420 | Unknown/GRE/1.5T | 0.5/2 neurologists, 1 neuroradiologist |
| Nagata et al, 201240 | Unknown/EPI/1.5T | Unknown/unknown |
| Nakata-Kudo et al, 200641 | Philips/GRE/1.5T | 1/1 neurologist, 1 radiologist |
| Park et al, 201342 | Philips/GRE/3T | 2/2 neurologists in consensus |
| Qiu et al, 201043 | GE Healthcare/EPI/1.5T | NA/1 neuroradiologist and subsequent raters |
| Staekenborg et al, 200944 | Siemens/GRE/1T | 1.5/unknown |
| Uetani et al, 201324 | Siemens/SWI/3T | NA/2 neuroradiologists in consensus |
| van der Vlies et al, 201245 | Siemens/GRE/1T or 1.5T | 1/unknown |
| Yates et al, 201446 | Siemens/SWI/3T | NA/2 neuroradiologists in consensus |
| Zonnefeld et al, 201447 | GE Healthcare/SWI/3T | NA/1 of 2 neuroradiologists |
| Postupdate | ||
| Olazarán et al, 201427 | GE Healthcare/EPI/3T | NR/neuroradiologist |
Note:—NA indicates not applicable; NR, examined but not reported.
a
Studies are excluded at the moderating factor analyses. Only the van der Vlies et al45 2012 study reported the percentage of medicated patients with AD.
b
Two different techniques were used with the same cohort.