Table 3:
Clinicoradiologic characteristics of patients with cSS
| Subject No. | Type of Dementia | Age (yr) | Sex | Location of cSS | Frontal | Temporal | Parietal | Occipital | Topographic Distribution of MBs | WMHa | ARWMC Rating Scaleb (R/L) |
||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Frontal | Temporal | Parieto-Occipital | |||||||||||
| 1 | AD | 79 | M | Right frontal | − | − | + | + | Mixed | 1 | 1/1 | 1/0 | 1/1 |
| 2 | AD | 81 | F | Left occipital | − | − | − | − | No MBs | 2 | 1/0 | 2/2 | 2/2 |
| Right occipital | |||||||||||||
| 3 | AD | 84 | M | Left temporal | − | + | − | − | Strictly lobar | 3 | 2/2 | 3/3 | 2/1 |
| 4 | AD | 83 | F | Left temporal | + | + | − | − | Strictly lobar | 2 | 2/2 | 2/2 | 2/2 |
| 5 | AD | 78 | F | Right temporal | − | + | + | + | Strictly lobar | 1 | 0/0 | 1/1 | 0/0 |
| 6 | AD | 80 | M | Right frontal | + | + | + | + | Strictly lobar | 2 | 2/2 | 2/2 | 2/2 |
| Right temporal | |||||||||||||
| 7 | AD | 78 | F | Right frontal | + | + | + | + | Strictly lobar | 1 | 0/1 | 1/0 | 1/1 |
| Right temporal | |||||||||||||
| 8 | AD | 70 | F | Right parietal | + | + | − | + | Strictly lobar | 1 | 1/1 | 1/1 | 1/1 |
| Right occipital | |||||||||||||
| 9 | DLB | 69 | F | Right frontal | + | − | + | − | Mixed | 2 | 2/2 | 2/2 | 2/2 |
| Right temporal | |||||||||||||
| 10 | VaD | 87 | M | Right frontal | + | + | − | + | Mixed | 2 | 1/1 | 2/2 | 2/2 |
| Right temporal | |||||||||||||
| Right occipital | |||||||||||||
| Left temporal | |||||||||||||
| Left occipital | |||||||||||||
| 11 | MCI | 82 | M | Right occipital | − | − | + | − | Mixed | 3 | 3/3 | 3/2 | 3/3 |
| Left occipital | |||||||||||||
| 12 | MCI | 80 | M | Left temporal | + | + | + | + | Mixed | 3 | 3/3 | 3/3 | 3/3 |
Note:—ARWMC indicates age-related white matter changes; R/L, right/left; WMH, white matter hyperintensities; VaD, vascular dementia.
a
WMH were graded according to the scale of Fazekas et al17: 0, absent; 1, punctate; 2, early confluent; and 3, confluent.
b
ARWMC rating scale18: 0, no lesions (including symmetric, well-defined caps, or bands); 1, focal lesions; 2, beginning confluence of lesions; 3, diffuse involvement of the entire region, with or without involvement of U fibers.