Fig 2.

Depiction of a leukocortical U-fiber lesion on sagittal FLAIR (A), FLAIR² (B), DIR (C), and a T1-weighted image (D) of a patient with relapsing-remitting MS (a 54-year-old man). The same lesion is clearly visible on all coronal images (a–d). Here, FLAIR and T2 were reconstructed to 0.3-mm³ isotropic imaging voxels (acquired at 0.6 × 0.68 × 1.2 mm³ in 7 minutes and 51 seconds and 7 minutes and 12 seconds, respectively), resulting in a visible SNR reduction, especially on FLAIR (A), and influencing the image quality of our FLAIR² (B).