Table 2.
Baseline characteristics of study groups.
| Variables | Study groups | P value | ||
|---|---|---|---|---|
| Healthy individuals | Stable patients | cAMR patients | ||
| eGFR1 (ml/min/1.73 m2) | 107.37 (9.50) | 74.76 (30.03) | 49.49 (33.01) | <0.001 |
| 109.00 [98.50; 113.50] | 79.71 [56.01; 97.70] | 39.72 [18.53; 82.42] | ||
|
| ||||
| Creatinine (mg/dl) | 0.81 (0.23) | 1.23 (0.68) | 3.30 (3.70) | <0.001 |
| 0.85 [0.60; 0.92] | 1.24 [1.09; 2.01] | 3.16 [2.01; 5.9] | ||
|
| ||||
| Urea (mg/dl) | 26.75 (8.75) | 41 (26) | 88 (75.5) | <0.001 |
| 27.00 [19.50; 31.75] | 44.00 [31.00; 58.50] | 86.5 [44.00; 123.50] | ||
|
| ||||
| BUN2 | 17.12 (6.49) | 25.98 (19.25) | 44.76 (24.22) | <0.001 |
| 18.50 [13.50; 21.25]s | 19.15 [14.01; 26.63] | 41.58 [28.50; 58.41]c | ||
|
| ||||
| TG3 (mg/dl) | 92.87 (33.15) | 161.79 (107.72) | 165.51 (73.97) | 0.192 |
| 94.50 [76.50; 110.25] | 140 [103.50; 175] | 147.00 [120.00; 203.00] | ||
|
| ||||
| Cholesterol (mg/dl) | 142.5 (42.59) | 149.42 (35.32) | 153.79 (56.69) | 0.919 |
| 125.00 [108.50; 189.50] | 141.00 [123.00; 172.00] | 143.00 [123.00; 186.50] | ||
|
| ||||
| HDL4 (mg/dl) | 48.37 (9.78) | 45.24 (20.08) | 48.82 (23.93) | 0.671 |
| 47.50 [43.75; 56.75] | 41.00 [31.00; 52.00] | 45.00 [37.00; 55.50] | ||
|
| ||||
| LDL5 (mg/dl) | 105.25 (20.28) | 89.38 (39.83) | 76.90 (26.12) | 0.624 |
| 110.00 [99.75; 115.50] | 80.00 [6.50; 105.50] | 75.00 [63.00; 98.00] | ||
|
| ||||
| WBC6 (103/μl) | 6.25 (1.28) | 6.54 (2.35) | 7.09 (5.66) | 0.756 |
| 6.25 [5.45; 7.12] | 6.10 [4.84; 8.35] | 6.17 [4.92; 8.31] | ||
|
| ||||
| RBC7 (106/μl) | 5.10 (0.77) | 4.25 (0.97) | 3.27 (1.16) | 0.003 |
| 5.00 [4.80; 5.80] | 4.10 [3.60; 4.81] | 3.31 [2.94; 4.00] | ||
|
| ||||
| Hb8 (g/dl) | 12.53 (1.18) | 12.62 (2.85) | 9.84 (1.77) | <0.001 |
| 12.2 [11.8; 13.35] | 12.80 [10.95; 14.55] | 9.60 [8.60; 11.20] | ||
|
| ||||
| Platelet (103/μl) | 295.00 (109.80) | 201.35 (77.29) | 168.78 (100.69) | 0.996 |
| 280.00 [212.5; 387.50] | 198.00 [149.0; 249.5] | 178.00 [121.50; 221.00] | ||
|
| ||||
| Lymphocyte (%) | 36.41 (5.62) | 21.20 (9.32) | 22.32 (9.70) | <0.001 |
| [32.00; 38.00] | 19.00 [14.00; 26.50] | 23.52 [16.00; 29.00] | ||
|
| ||||
| FBS9 (mg/dl) | 106.12 (7.88) | 113.94 (54.84) | 119.57 (72.89) | 0.882 |
| 104 [99.75; 111.00] | 97.00 [88.00; 104.50] | 97.00 [86.00; 115.25] | ||
|
| ||||
| Calcium (mg/dl) | 9.27 (0.83) | 11.66 (15.65) | 10.34 (10.67) | 0.051 |
| 9.10 [8.87; 10.00] | 9.25 [8.70; 9.67] | 8.75 [8.27; 9.22] | ||
|
| ||||
| Phosphor (mg/dl) | 3.83 (0.76) | 3.75 (1.20) | 6.36 (8.18) | <0.001 |
| 3.70 [3.30; 4.50] | 3.60 [3.00; 4.10] | 4.85 [3.87; 6.00] | ||
|
| ||||
| Sodium (mEq/l) | 140.00 (3.92) | 103.44 (3.07) | 137.85 (5.33) | 0.016 |
| 139.5 [136.75; 144.00] | 141.00 [138.85; 142.00] | 138.00 [136.00; 141.00] | ||
|
| ||||
| Potassium (mEq/l) | 5.20 (1.11) | 4.39 (0.93) | 4.68 (0.98) | 0.062 |
| 5.30 [4.90; 6.00] | 4.15 [3.92; 4.56] | 4.60 [4.17; 5.04] | ||
|
| ||||
| AST10 (U/l) | 26.75 (10.67) | 21.30 (6.75) | 18.97 (10.80) | 0.027 |
| 29.00 [17.25; 33.75] | 21.00 [16.00; 27.00] | 15.50 [11.75; 24.00] | ||
|
| ||||
| ALT11 (U/l) | 32.25 (14.28) | 31.05 (27.05) | 26.15 (30.75) | 0.034 |
| 34.5 [20.50; 42.00] | 26.00 [16.00; 32.00] | 15.50 [12.75; 24.00] | ||
Values were expressed as mean (standard deviation) and median [Q1; Q3]. 1Estimated glomerular filtration rate. 2Blood urea nitrogen. 3Triglyceride. 4High density lipoproteins. 5Low density lipoproteins. 6White blood cells. 7Red blood cell. 8Hemoglobin. 9Fasting blood sugar. 10Aspartate aminotransferase. 11Alanine aminotransferase.