Fig. 2.

Histopathologic images from COVID-19 patients showing endothelial injury and thrombus, which is similar to the histopathology seen in populations living in regions with high air pollution. (A) Histopathologic findings from COVID-19 patients show acute lung injury with hyaline membrane in the alveolar space. (B) Vascular damage with microthrombi in lung small vessels. (C) Cases show, airway inflammation in trachea sections with polymorphous inflammatory infiltrate of submucosal layers. (D) Pulmonary thromboembolus is also seen in many COVID-19 patients. Photos A–C from Calabrese et al. in Virchows Arch. 2020 and D from Vasquez-Bonilla et al. in Hum. Pathol. 2020 under the Creative Commons license (Calabrese et al., 2020; Vasquez-Bonilla et al., 2020).