A 52-year-old woman with a diffuse astrocytoma without IDH mutation. A, Axial T2WI demonstrates heterogeneous high signal intensity with indistinct borders on the left temporal lobe. B, Contrast-enhanced axial T1-weighted image demonstrates a lesion enhancement with blurred borders. C, A corresponding ADC map shows the tumor with a decreased ADC value (ADCmin = 0.684 × 10−3 mm2/s, rADC = 1.08). D, Correlative color CBV image shows elevated perfusion with the calculated rCBVmax of 3.10.