Fig 2.

Correlations in patients with ALS between morphometric parameters (thickness and signal intensity of deeper layers of M1) and clinical scores (UMN score, DPR, and ALSFRS-R). The UMN score ranges from zero to 8 because it refers to a single limb and not to the overall evaluation. Correlations between morphometric parameters and UMN score were calculated by taking into account the clinical score of each limb of every patient and signal intensity and thickness of the corresponding areas of M1.