Table 1:
Group 1 (n = 38) | Group 2 (n = 25) | Group 3 (n = 25) | Group 4 (n = 5) | Fisher Exact Test, P Value | |
---|---|---|---|---|---|
Percentage inhibitionb | |||||
Median | 37.5 | 17.0 | 30.0 | 30.0 | .32 |
IQR | 17.0–70.0 | 6.0–47.0 | 12.0–47.0 | 24.0–54.0 |
Group 1: CYP2C19*1/*1; Group 2: CYP2C19*1/*2,*1/*3, *2/*2, *2/*3; Group 3: CYP2C19*1/*17,*17/*17; Group 4: CYP2C19*2/*17.
Percentage inhibition = (BASE − PRU) × 100/BASE.