Axial images from the brain of a 59-year-old woman with mixed features of response, including areas of treatment-related changes and TP. Contrast-enhanced T1-weighted image (A) shows a new enhancing lesion in the left parietal lobe. The lesion shows slightly elevated perfusion on the CBV map (B) and lower MD (C). Lower FA (D), CL (E), CP (F), and higher CS (G) values from the enhancing part are noticed relative to the normal white matter. The imaging appearance looks similar to that of PsP (Fig 1). Photomicrograph of a histologic section (H, hematoxylin-eosin stain, 50× magnification) has similar amounts of treatment-related changes (50%) and viable tumor (50%).