Fig 1.

Regions of injury involving the corpus callosum and fornix/septohippocampal circuit among patients with posttraumatic migraine headaches. Images derived from Tract-Based Spatial Statistics results and rendered on T1-weighted images from the Montreal Neurological Institute atlas show common regions of injury involving the corpus callosum and fornix/septohippocampal circuit in patients with posttraumatic migraine headaches. ROIs involving the FSHC and CC corresponding to voxels of significant difference in FA (P < .05 corrected for multiple comparisons) between controls (subjects with mTBI without PTM) and patients with mTBI with PTM in are shown overlaid on the white matter skeleton (blue). ROIs corresponding to voxels of significantly decreased FA in patients with mTBI with PTM are shown in red in the axial (A), coronal (B), and sagittal (C) planes.