Table 1:
Univariate comparison between patients with good and poor outcomesa
| Good Outcome (mRS ≤2) (n = 68) | Poor Outcome (mRS > 2) (n = 41) | Test Value | P Value | |
|---|---|---|---|---|
| Age (yr) | 66.1 ± 12.7 | 72.0 ± 12.4 | t = −2.36 | .02c |
| Female (No.) (%) | 21 (30.9) | 19 (46.3) | χ2 = 2.63 | .15 |
| Risk factors | ||||
| Hypertension (No.) (%) | 46 (67.6) | 29 (70.1) | χ2 = 0.11 | .83 |
| Diabetes mellitus (No.) (%) | 12 (17.6) | 13 (31.7) | χ2 = 2.86 | .10 |
| Atrial fibrillation (No.) (%) | 21 (30.9) | 21 (51.2) | χ2 = 4.47 | .04c |
| Smoking (No.) (%) | 30 (44.1) | 13 (31.7) | χ2 = 1.65 | .23 |
| Previous stroke/TIA (No.) (%) | 11 (16.2) | 6 (14.6) | χ2 = 0.05 | 1.00 |
| Large-artery occlusion (No.) (%) | 28 (41.2) | 32 (78.0) | χ2 = 14.05 | <.001c |
| Baseline SBP (mm Hg) | 155.4 ± 20.5 | 151.0 ± 24.9 | t = 0.64 | .53 |
| Baseline DBP (mm Hg) | 87.1 ± 17.1 | 83.2 ± 14.8 | t = 1.21 | .23 |
| ONT (min) | 251.2 ± 74.8 | 235.1 ± 73.4 | t = −1.11 | .27 |
| Baseline glucose level (mmol/L) | 7.7 ± 2.6 | 8.1 ± 2.7 | t = −0.77 | .44 |
| Baseline NIHSS score | 6.0 (3.0–10.0) | 14.0 (8.5–18.0) | Z = −5.11 | <.001c |
| Baseline diffusion lesion volume (mL) | 1.0 (0–14.2) | 8.4 (2.9–51.2) | Z = −3.12 | .002c |
| Baseline hypoperfusion volume (mL) | 22.7 (3.0–74.6) | 81.8 (31.9–166.6) | Z = −4.16 | <.001c |
| SDR of TSV (%) | 1.2 (−2.6–3.6) | 5.8 (−1.1–8.9) | Z = −2.61 | .009c |
| SDR of SV (%) | −0.3 (−2.4–2.6) | 0.1 (−3.0–3.7) | Z = −0.45 | .65 |
| SDR of ICV (%) | −0.1 (−4.1–3.5) | 0.9 (−5.1–5.7) | Z = −.71 | .48 |
| Proportion of penumbral tissue loss (%)b | 1.3 (0–19.9) | 38.4 (4.9–95.3) | Z = −4.23 | <.001c |
| Infarct volume at 24 hr (mL) | 4.2 (1.0–9.9) | 38.8 (11.5–107.0) | Z = −5.54 | <.001c |
Note:—SBP indicates systolic blood pressure; DBP, diastolic blood pressure; ONT, onset-to-needle time.
a
Table cells express results in mean ± SD for normally distributed continuous variables, No. (%) for dichotomous variables, and median (interquartile range) for ordinal variables and non-normally distributed continuous variables, respectively.
b
Proportion of Penumbral Tissue Loss = 100 × (Posttreatment Infarct Volume − Pretreatment Infarct Volume)/(Pretreatment Hypoperfusion Volume − Pretreatment Infarct Volume).
c
P < .05.