Table 5:
Comparison between children with and without arthrogryposis regarding some of the brain abnormalities found on MRIa
| Variables | Arthrogryposis |
Pb | |
|---|---|---|---|
| No (n = 8) | Yes (n = 4) | ||
| Decreased brain volume | 6 (75.0%) | 4 (100.0%) | .515 |
| Grade of brain volume decrease | |||
| Mild | 1 (20.0%) | 0 (0.0%) | .876 |
| Moderate/severe | 4 (80.0%) | 3 (100.0%) | |
| Degree of cerebral damage | .394 | ||
| Absent | 1 (12.5%) | 0 (0.0%) | |
| Mild | 2 (25.0%) | 0 (0.0%) | |
| Moderate | 2 (25.0%) | 0 (0.0%) | |
| Severe | 3 (37.5%) | 4 (100.0%) | |
| Symmetry | 6 (75.0%) | 3 (75.0%) | >.999 |
| Cortical development abnormalities | |||
| Pachygyria | 3 (37.5%) | 3 (75.0%) | .545 |
| Polymicrogyria | 2 (25.0%) | 0 (0.0%) | .515 |
| Simplified gyral pattern | 4 (50.0%) | 3 (75.0%) | .576 |
| Corpus callosum | >.999 | ||
| Normal | 2 (25.0%) | 0 (0.0%) | |
| Hypogenesis | 5 (62.5%) | 3 (75.0%) | |
| Hypoplasia | 1 (12.5%) | 1 (25.0%) | |
| Cortical and subcortical junction calcifications | 7 (85.5%) | 4 (100.0%) | >.999 |
| Basal ganglia calcifications | 3 (37.5%) | 3 (75.0%) | .545 |
| Periventricular calcifications | 0 (0.0%) | 3 (75.0%) | .018c |
| Brain stem calcifications | 1 (12.5%) | 3 (75.0%) | .067 |
| Cerebellum calcifications | 0 (0.0%) | 2 (50.0%) | .091 |
| Cerebellum or brain stem hypoplasia | 2 (25.0%) | 4 (100.0%) | .061 |
| Increased cisterna magna | 8 (100.0%) | 4 (100.0%) | – |
| Delayed myelination | 5 (50.0%) | 4 (100.0%) | .208 |
a
Data are number of patients (%).
b
P = Fisher Exact test.