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A 26-year-old man presenting with clinically isolated syndrome. A small enhancing lesion located in the right temporal subcortical white matter is seen on the 2 cumulative-dose contrast-enhanced T1-weighted scans (arrows in C and D) but is initially missed on the 2 single-dose scans. Mild enhancement is seen in the early and delayed single-dose scans (arrows in A and B) only in retrospect.
