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. 2021 Jan 29;100(4):e24441. doi: 10.1097/MD.0000000000024441

Table 1.

Baseline characteristics of patients with COVID-19.

Variables Entire cohort (n = 145) Training cohort (n = 97) Validation cohort (n = 48) P value
Sex (male, n%) 70 (48.28%) 49 (50.52%) 21 (43.75%) .44
Age (y) 69.00 (63.00, 78.00) 69.00 (63.50, 77.50) 69.50 (62.00, 78.75) .80
Comorbidities 104 (71.72%) 72 (74.23%) 32 (66.67%) .34
 Hypertension 67 (46.21%) 43 (44.33%) 24 (50.00%) .52
 Diabetes 27 (18.62%) 22 (22.68%) 5 (10.42%) .07
 Coronary heart disease 19 (13.10%) 14 (14.43%) 5 (10.42%) .50
 Chronic obstructive pulmonary disease 13 (8.97%) 10 (10.31%) 3 (6.15%) .42
 Cerebrovascular disease 12 (8.28%) 7 (7.22%) 5 (10.42%) .51
White blood cell count (×109/L) 7.20 (5.45, 10.50) 6.73 (5.38, 9.75) 7.68 (5.80, 12.60) .09
Neutrophil count (×109/L) 5.46 (3.42, 8.72) 5.27 (3.30, 8.31) 5.94 (4.03, 10.33) .15
Lymphocyte count (×109/L) 0.94 (0.56, 1.36) 0.89 (0.56, 1.32) 1.06 (0.54, 1.39) .29
Haemoglobin (g/L) 115.60 ± 19.96 115.04 ± 21.02 116.73 ± 17.77 .63
Platelet count (×109/L) 205.05 ± 98.65 199.43 ± 93.94 216.40 ± 107.68 .33
Albumin (g/L) 32.52 ± 4.56 32.45 ± 4.24 32.66 ± 5.19 .81
Alanine aminotransferase (U/L) 23.60 (15.21, 45.90) 21.10 (14.75, 46.75) 25.95 (17.39, 45.30) .42
Aspartate aminotransferase (U/L) 24.31 (16.95, 39.02) 23.80 (16.85, 39.80) 26.05 (16.87, 39.03) .71
Alkaline phosphatase (U/L) 76.60 (62.70, 98.50) 76.20 (64.66, 98.50) 77.21 (56.65, 99.74) .59
Glutamyl transpeptidase (U/L) 34.70 (21.20, 58.20) 34.00 (20.45, 56.70) 36.25 (25.12, 74.93) .50
Total bilirubin (μmol/L) 11.20 (8.40, 17.30) 11.80 (8.55, 18.00) 10.64 (8.03, 14.43) .14
Urea nitrogen (mmol/L) 5.24 (3.82, 8.05) 5.15 (3.86, 7.44) 6.21 (3.80, 8.92) .35
Creatinine (μmol/L) 67.60 (54.35, 86.40) 68.20 (54.87, 87.67) 64.83 (53.20, 84.68) .49
Lactate dehydrogenase (U/L) 278.70 (198.95, 414.75) 293.00 (207.25, 442.94) 261.50 (170.95, 380.30) .13
Creatine kinase (U/L) 54.00 (31.20, 89.60) 51.90 (30.90, 89.60) 57.45 (31.95, 89.60) .96
C-reactive protein (mg/L) 29.31 (3.23, 84.15) 37.43 (3.48, 89.36) 27.19 (2.58, 78.79) .76
Prothrombin time (s) 13.70 (12.60, 15.47) 13.87 (12.60, 15.68) 13.44 (12.50, 15.45) .43
Activated partial thromboplastin time (s) 28.29 (26.05, 30.74) 28.46 (26.22, 30.74) 28.26 (25.82, 30.93) .99
D-dimer (mg/L) 1.54 (0.62, 3.36) 1.54 (0.68, 3.35) 1.54 (0.56, 3.39) .64
Death (n%) 57 (39.31%) 39 (40.21%) 18 (37.50%) .75

COVID-19, corona virus disease 2019. P value was the result of comparison between training set and validation set.

Pearson Chi-Squared test.

t test.

Mann–Whitney test.