Table 1.
High confidence putative Ari-1 substrates
| Namea | MW (kDa) | FC | p-value | Unique peptides | Biological process | Orthologueb |
|---|---|---|---|---|---|---|
| PPO1 | 79 | 101.70 | 3.03E-04 | 7 | Dopamine metabolic process | - |
| Vha44 | 92 | 7.46 | 2.81E-04 | 3 | Proton transmembrane transport | ATP6V1C1 |
| CG15117 | 71 | 5.69 | 3.05E-02 | 2 | Carbohydrate metabolic process | GUSB |
| CG6424 | 88 | 4.35 | 2.63E-02 | 6 | - | FAM13A |
| Oscillin | 29 | 3.66 | 1.09E-04 | 3 | Glucosamine catabolic process | GNPDA2 |
| Rh6 | 41 | 3.62 | 1.63E-03 | 2 | Phototransduction | OPN4 |
| CG32486 | 45 | 2.88 | 3.72E-03 | 6 | - | CYHR1 |
| Lsp1β | 95 | 2.82 | 1.95E-02 | 2 | - | - |
| GstO3 | 27 | 2.61 | 1.62E-03 | 2 | Glutathione metabolic process | GSTO1 |
| CG4629 | 63 | 2.52 | 3.82E-03 | 11 | Protein phosphorylation | NIM1K |
| Rh4 | 42 | 2.47 | 6.32E-03 | 6 | Phototransduction | OPN4 |
| Comt | 82 | 2.41 | 1.68E-05 | 26 | SNARE complex disassembly | NSF |
| EIF-1A | 17 | 2.28 | 2.28E-03 | 4 | Translation | EIF1AY |
| Prosα7 | 27 | 2.27 | 2.45E-03 | 8 | Proteasomal catabolic process | PSMA3 |
| CG32687 | 41 | 2.27 | 1.95E-02 | 3 | - | LRRC58 |
| Vha68-1 | 68 | 2.05 | 4.29E-03 | 16 | Proton transmembrane transport | ATP6V1A |
Fly protein names. sizes (MW), unique peptides, and the biological process they are involved in are reported. ari-1OE/control fold changes (FC) and its statistical significance (p-value) are also given. The complete data set, as well as all GlyGly peptides, is available as Supporting information in Table S1.
a
Given according to Flybase nomenclature (https://flybase.org/).
b
Humna orthologues with the best Flybase score are provided.